Internal research and development expenses Internal Research and Development Expenses [Member] Internal Research and Development Expenses Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Statistical Measurement Statistical Measurement [Domain] 2030 to 2035 Lessee, Operating Lease, Liability, to be Paid, after Year Five Award Timing Predetermined Award Timing Predetermined [Flag] Related Party Transaction [Axis] Related Party Transaction [Axis] Stock-based compensation Effective Income Tax Rate Reconciliation, Tax Expense (Benefit), Share-Based Payment Arrangement, Percent Entity File Number Entity File Number Additional paid-in capital Additional Paid-in Capital [Member] Impairment of Long-Lived Assets Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block] Performance obligation satisfied Contract with Customer, Performance Obligation Satisfied in Previous Period Tabular List, Table Tabular List [Table Text Block] Additions based on tax positions related to prior period Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions Recently Adopted Accounting Pronouncements and Recent Accounting Pronouncements Not Yet Adopted New Accounting Pronouncements, Policy [Policy Text Block] Regulatory milestone payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Regulatory Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Regulatory Milestones Fair Value Measurements Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block] Accounts payable Increase (Decrease) in Accounts Payable Shares available for future equity grants Share-Based Payment Arrangement [Member] Unrealized loss Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Software in progress Software In Progress [Member] Software in progress. Net loss per share, basic (in USD per share) Earnings Per Share, Basic Adjustment to Compensation: Adjustment to Compensation [Axis] Related Party Transactions Related Party Transactions Disclosure [Text Block] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Total common stock reserved for future issuance (in shares) Common stock, capital shares reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Target licensing and reservation payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Target Licensing And Reservation Revenue, Remaining Performance Obligation, Variable Consideration Amount, Target Licensing And Reservation Stock-based compensation Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost Gross deferred tax assets Deferred Tax Assets, Gross Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Equity Distribution Agreement Equity Distribution Agreement [Member] Equity distribution agreement. Schedule of Disaggregated Research and Development Expenses Schedule of Segment Reporting Information, by Segment [Table Text Block] Issuance under employee stock purchase plan (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Equity distribution agreement, commission percentage on gross sales price of shares Commission Percentage On Gross Sales Price Of Shares Commission percentage on gross sales price of shares. Adjustment to Compensation, Amount Adjustment to Compensation Amount Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Options to purchase common stock issued and outstanding Options Share-Based Payment Arrangement, Option [Member] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Research and Development Expenses Research and Development Expense, Policy [Policy Text Block] Included in cash and cash equivalents Cash and Cash Equivalents [Member] Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Remaining stock available for sale Sale Of Stock, Common Stock Remaining Available For Sale, Value Sale Of Stock, Common Stock Remaining Available For Sale Antidilutive Securities Antidilutive Securities [Axis] Total stockholders’ equity Beginning Balance Ending Balance Equity, Attributable to Parent Other comprehensive loss, net of tax: Other Comprehensive Income (Loss), Net of Tax [Abstract] Insider Trading Policies and Procedures [Line Items] Total stock-based compensation Share-Based Payment Arrangement, Expense Schedule of Property and Equipment Property, Plant and Equipment [Table Text Block] Common stock, shares authorized (in shares) Common stock, shares authorized to issue (in shares) Common Stock, Shares Authorized Exercise of pre-funded warrants (in shares) Stock Issued During Period, Shares, Warrants Exercised Stock Issued During Period, Shares, Warrants Exercised Issuance of common stock and pre-funded warrants, net of issuance costs (in shares) Issuance of common stock in "at the market" financing, net of issuance costs (in shares) Stock Issued During Period, Shares, New Issues Current assets: Assets, Current [Abstract] Operating lease liabilities Deferred Tax Assets Operating Lease Liabilities Deferred tax assets operating lease liabilities. Number of options outstanding, options forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Total liabilities and stockholders’ equity Liabilities and Equity Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Extension payment Proceeds from Collaboration Agreement, Extension Payment Proceeds from Collaboration Agreement, Extension Payment Number of options outstanding Number of RSUs Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Total cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation Liabilities and stockholdersʼ equity Liabilities and Equity [Abstract] State Authorities State and Local Jurisdiction [Member] Audit Information [Abstract] Audit Information Cover [Abstract] Cover [Abstract] Maximum Maximum [Member] General and administrative General and Administrative Expense [Member] Weighted-average exercise price, options exercisable as of November 30, 2024 (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price Accounting Policies [Abstract] Accounting Policies [Abstract] Interest on unrecognized tax benefits Unrecognized Tax Benefits, Interest on Income Taxes Accrued Total Debt Securities, Available-for-Sale, Unrealized Loss Position Schedule of Undiscounted Future Non-Cancellable Lease Payments Schedule Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Restricted stock units issued and outstanding Restricted Stock [Member] Internal-Use Software Development Costs Internal Use Software, Policy [Policy Text Block] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Loss on disposal of property and equipment Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property Fair value of RSUs vested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Pay vs Performance Disclosure [Line Items] Class of Warrant or Right [Axis] Class of Warrant or Right [Axis] Total operating lease liabilities Total operating lease liabilities Operating Lease, Liability U.S. government agency securities US Government Agencies Debt Securities [Member] Term extension Collaboration Agreement Contract Term, Extension Collaboration Agreement Contract Term, Extension Retirement Benefits [Abstract] Retirement Benefits [Abstract] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Depreciation and amortization Depreciation, Depletion and Amortization, Nonproduction Loss before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Entity Shell Company Entity Shell Company Stock Option, RSUs and ESPP Stock Options Restricted Stock Units And Employee Stock Purchase Plan [Member] Stock options restricted stock units and employee stock purchase plan. Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Capitalized stock-based compensation related to internal-use software development Share-Based Payment Arrangement, Amount Capitalized Accrued expenses and other current liabilities Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Drug targets Number Of Specified Drug Targets Number Of Specified Drug Targets Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Company Selected Measure Amount Company Selected Measure Amount 2028 Lessee, Operating Lease, Liability, to be Paid, Year Three Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Less: tenant improvement allowance Lessee, Operating Lease, Liability, Tenant Improvement Allowance Lessee, Operating Lease, Liability, Tenant Improvement Allowance Proceeds from exercise of stock options and pre-funded warrants Proceeds From Stock Options And Warrants Exercised Proceeds From Stock Options And Warrants Exercised Total comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Issuance of pre funded warrants Stock Issued During Period, Value, New Issues And Adjustments To Additional Paid In Capital, Warrant Issued Stock Issued During Period, Value, New Issues And Adjustments To Additional Paid In Capital, Warrant Issued Name Measure Name Schedule of Components of Loss Before Income Taxes Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block] Upfront payment of additional fees Upfront Payment Of Additional Fees Upfront payment of additional fees. Domestic Income (Loss) from Continuing Operations before Income Taxes, Domestic Schedule of Stock-Based Compensation Expense Related to Stock Options RSUs and ESPP Included in Statements of Operations Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Operating lease liabilities, current Operating Lease, Liability, Current Class Of Stock [Line Items] Class of Stock [Line Items] Impairment losses Marketable Security, Realized Gain (Loss) Software Software and Software Development Costs [Member] Document Fiscal Period Focus Document Fiscal Period Focus 2020 Equity Incentive Plan Two Thousand Twenty Equity Incentive Plan [Member] Two thousand twenty equity incentive plan. Award Timing Method Award Timing Method [Text Block] Amortized cost Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss Furniture and fixtures Furniture and Fixtures [Member] Award Type Award Type [Axis] Deferred revenue, net of current portion Contract with Customer, Liability, Noncurrent Total assets Assets Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Stock-Based Compensation Share-Based Payment Arrangement [Policy Text Block] Trading Symbol Trading Symbol 2029 Lessee, Operating Lease, Liability, to be Paid, Year Four Weighted-average grant date fair value, RSUs vested (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Restricted Cash Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block] Geographical [Domain] Geographical [Domain] Change in valuation allowance Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent Income taxes Income Tax, Policy [Policy Text Block] Entity Address, City or Town Entity Address, City or Town Cash flows from operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Organization Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block] Research and development tax credits Effective Income Tax Rate Reconciliation, Tax Credit, Research, Percent Pre-funded warrants issued and outstanding Pre Funded Warrants Member [Member] Pre Funded Warrants Member Cash paid for amounts included in the measurement of lease liabilities: Additional Cash Flow Elements and Supplemental Cash Flow Information [Abstract] Total deferred tax assets Deferred Tax Assets, Net of Valuation Allowance Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Income Statement Location Statement of Income Location, Balance [Domain] Restricted stock units issued and outstanding Restricted Stock Units (RSUs) [Member] Reconciliation of cash, cash equivalents and restricted cash: Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation [Abstract] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Number of renewal options Lessee, Operating Lease, Number Of Renewal Options Lessee, Operating Lease, Number Of Renewal Options Entity Emerging Growth Company Entity Emerging Growth Company Common stock, dividends declared (in USD per share) Common Stock, Dividends, Per Share, Declared Impairment losses Impairment, Long-Lived Asset, Held-for-Use Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding NX-1607 NX-1607 [Member] NX-1607 Right-of-use assets recognized in exchange for lease obligations Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Number of options outstanding, beginning balance (in shares) Number of options outstanding, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Expiration term Collaboration Agreement Expiration Term Collaboration Agreement Expiration Term Level 2 Fair Value, Inputs, Level 2 [Member] Document Financial Statement Error Correction [Flag] Document Financial Statement Error Correction [Flag] Income Tax Examination [Line Items] Income Tax Examination [Line Items] Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Schedule of Provision for Income Taxes Schedule of Components of Income Tax Expense (Benefit) [Table Text Block] Plan Name Plan Name [Axis] Property and Equipment Property, Plant and Equipment, Policy [Policy Text Block] PEO PEO [Member] Maturities of marketable securities Proceeds from Sale, Maturity and Collection of Investments Supplemental disclosures of non-cash investing and financing activities: Noncash Investing and Financing Items [Abstract] Issuance costs related to equity financing included in accrued expenses and other current liabilities Issuance Costs Related to Equity Financing Included in Accrued Expenses and Other Current Liabilities Issuance Costs Related to Equity Financing Included in Accrued Expenses and Other Current Liabilities Increase in valuation allowance Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount Shares issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Expected volatility Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate Accumulated deficit Retained Earnings [Member] Accrued expenses and other current liabilities Accrued Expenses And Other Liabilities Current Accrued expenses and other liabilities current. Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Income Tax Authority Income Tax Jurisdiction [Axis] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Share-based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Income Statement [Abstract] Income Statement [Abstract] Provision for income taxes Income Tax Expense (Benefit) Greater than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer Clinical milestone payment Proceeds From Collaboration Agreement, Clinical Milestone Payment Proceeds From Collaboration Agreement, Clinical Milestone Payment Purchases of marketable securities Payments to Acquire Marketable Securities Sale of Stock Sale of Stock [Domain] Accrued taxes Taxes Payable, Current Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Product and Service [Domain] Product and Service [Domain] Fair Value Debt Securities, Available-for-Sale [Abstract] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] Rent payable per month Operating Lease Rent Payable Adjustment, Per Month Operating lease rent payable per month. Total property and equipment, gross Property, Plant and Equipment, Gross Cash and short-term investments Cash, Cash Equivalents, and Short-Term Investments Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Proceeds from issuances of common stock and pre-funded warrants, net of issuance costs Proceeds From Issuance Of Common Stock And Warrants Proceeds From Issuance Of Common Stock And Warrants Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Amortization of operating lease right-of-use assets Operating Lease, Right-of-Use Asset, Periodic Reduction Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Internal-Use Software Development Costs Internal Use Software Development Costs [Member] Internal-use software development costs. City Area Code City Area Code Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] All Trading Arrangements All Trading Arrangements [Member] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Weighted-average contractual life, options vested and expected to vest as of November 30, 2024 (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Number of RSUs, beginning balance (in shares) Number of RSUs, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Cash flows from investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] General and administrative General and Administrative Expense Total compensation cost related to stock-based awards yet to recognize Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Related Party Transactions [Abstract] Related Party Transactions [Abstract] Estimated fair value Debt Securities, Available-for-Sale, Excluding Accrued Interest Property and equipment, useful life Property, Plant and Equipment, Useful Life Preferred stock, par value (in USD per share) Preferred Stock, Par or Stated Value Per Share Subsequent Event Subsequent Event [Member] Schedule of ESPP Assumptions Schedule of Share-Based Payment Award, Stock Options, Valuation Assumptions [Table Text Block] Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Schedule of Operating Expense and Sublease Income Lease, Cost [Table Text Block] PEO Total Compensation Amount PEO Total Compensation Amount Weighted-average exercise price, options vested and expected to vest as of November 30, 2024 (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Money market funds Money Market Funds [Member] Equity Components Equity Components [Axis] Property Plant And Equipment [Line Items] Property, Plant and Equipment [Line Items] Reconciliation of Unrecognized Tax Benefits, Excluding Amounts Pertaining to Examined Tax Returns [Roll Forward] Unrecognized Tax Benefits [Roll Forward] Auditor name Auditor Name Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Number of reportable segments Number of Reportable Segments Interest and other income, net Interest and Other Income Other Performance Measure, Amount Other Performance Measure, Amount Weighted- average exercise price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Entity Address, State or Province Entity Address, State or Province Marketable Securities Marketable Securities, Policy [Policy Text Block] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Related Party Related and Nonrelated Parties [Domain] Total current liabilities Liabilities, Current Area of office space leased Area Of Office Space Leased Area of office space leased. Over-Allotment Option Over-Allotment Option [Member] Individual: Individual [Axis] Organization Consolidation And Presentation Of Financial Statements [Line Items] Organization Consolidation And Presentation Of Financial Statements [Line Items] Organization, consolidation and presentation of financial statements. Contribution expense Defined Contribution Plan, Cost Fair Value of Financial Instruments Fair Value of Financial Instruments, Policy [Policy Text Block] Income Tax Authority Income Tax Jurisdiction [Domain] Document Annual Report Document Annual Report Research and development Research and Development Expense [Member] Additional paid-in capital Additional Paid in Capital, Common Stock Net cash provided by (used in) investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Working capital Working Capital working capital Document Fiscal Year Focus Document Fiscal Year Focus Basis of Presentation and Principles of Consolidation Basis of Accounting, Policy [Policy Text Block] Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Total Effective Income Tax Rate Reconciliation, Percent Entity Interactive Data Current Entity Interactive Data Current Plan Name Plan Name [Domain] Total compensation cost related to stock-based awards, recognition period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Schedule of Common Stock Shares Reserved for Future Issuance Schedule Of Common Stock Shares Reserved For Future Issuance [Table Text Block] Schedule of common stock shares reserved for future issuance. Exercise of stock options (in shares) Number of options outstanding, options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Deferred revenue Deferred Tax Assets, Deferred Income Valuation allowance Deferred Tax Assets, Valuation Allowance Aggregate intrinsic value, options exercisable as of November 30, 2024 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value Piper Sandler & Co. Piper Sandler And Co [Member] Piper Sandler & Co. Segment Information Segment Reporting Disclosure [Text Block] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] U.S. treasury securities US Treasury Securities [Member] Certain sales milestones payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Certain Sales Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Certain Sales Milestones Net operating loss carryforwards Deferred Tax Assets, Operating Loss Carryforwards Federal Current Federal Tax Expense (Benefit) Long-Lived Tangible Asset Long-Lived Tangible Asset [Axis] Other Commitments [Line Items] Other Commitments [Line Items] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Extended research term Contractual Extended Research Period Contractual extended research period. Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value, Recurring and Nonrecurring [Table] Leases Lessee, Leases [Policy Text Block] Exercise of pre-funded warrants Stock Issued During Period, Value, Warrants Exercised Stock Issued During Period, Value, Warrants Exercised Other assets Other Assets, Noncurrent Entity Central Index Key Entity Central Index Key PEO Name PEO Name Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Arrangement Duration Trading Arrangement Duration Schedule of Segment Reporting Information, by Segment [Table] Schedule of Segment Reporting Information, by Segment [Table] Expected volatility, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum Computer equipment Computer Equipment [Member] Deferred revenue, current Contract with Customer, Liability, Current Segments [Axis] Segments [Axis] Exercise price of warrants (in USD per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Local Phone Number Local Phone Number Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Federal statutory income tax rate Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent Subsequent Event Type [Axis] Subsequent Event Type [Axis] Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Assets Assets [Abstract] Total accrued expenses and other current liabilities Accrued And Other Liabilities Current Accrued and other liabilities current. Underlying Security Market Price Change Underlying Security Market Price Change, Percent Amortized cost, short-term Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss, Current Class of Warrant or Right [Domain] Class of Warrant or Right [Domain] Laboratory equipment Laboratory Equipment [Member] Laboratory equipment. Weighted-average grant date fair value, RSUs forfeited (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Deferred tax assets: Deferred Tax Assets, Net [Abstract] Stockholders’ equity: Equity, Attributable to Parent [Abstract] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Entity Address, Address Line One Entity Address, Address Line One Research and development Total research and development expenses Research and Development Expense Accumulated other comprehensive income (loss) AOCI Attributable to Parent [Member] Deferred Offering Costs Deferred Charges, Policy [Policy Text Block] Operating lease liabilities, net of current portion Operating Lease, Liability, Noncurrent Entity Voluntary Filers Entity Voluntary Filers Balance Sheet Related Disclosures [Abstract] Balance Sheet Related Disclosures [Abstract] Reportable Segment Reportable Segment [Member] Reportable Segment Repurchase of unvested early exercised stock options Payments For Repurchase Of Stock Options Payments For Repurchase Of Stock Options Fair Value as of Grant Date Award Grant Date Fair Value Entity Registrant Name Entity Registrant Name Summary Of Significant Accounting Policies [Table] Summary Of Significant Accounting Policies [Table] Summary of significant accounting policies. Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] NOL carryforwards Operating Loss Carryforwards Collaboration revenue Collaboration Revenue [Member] Collaboration Revenue RSUs granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Vesting of early exercised stock options Vesting Of Early Exercised Stock Options Vesting of early exercised stock options. RSUs forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Regulated Operations [Abstract] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Less than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Issuance of common stock Issuance costs, common stock Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Accrued interest receivable Interest Receivable, Current Counterparty Name Counterparty Name [Domain] 2027 Lessee, Operating Lease, Liability, to be Paid, Year Two Number of operating segments Number of Operating Segments Net accretion of discount on marketable securities Accretion (Amortization) of Discounts and Premiums, Investments Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Weighted-average contractual life (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Income Tax Examination [Table] Income Tax, Examination [Table] Related Party Related and Nonrelated Parties [Axis] Weighted-average grant date fair value, RSUs granted (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Title Trading Arrangement, Individual Title Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Restatement Determination Date: Restatement Determination Date [Axis] Non-PEO NEO Non-PEO NEO [Member] Aggregate intrinsic value, beginning balance Aggregate intrinsic value, ending balance Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Percentage of total combined voting power of common stock, percent Share Based Compensation Arrangement By Share Based Payment Award Combined Voting Power Of Common Stock Holding Percentage Share based compensation arrangement by share based payment award combined voting power of common stock holding percentage. Issuance of common stock under employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan Sale of Stock Sale of Stock [Axis] Unrealized gain Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Name Trading Arrangement, Individual Name Award Type Award Type [Domain] Sanofi Agreement Sanofi Agreement [Member] Sanofi agreement. 2026 Lessee, Operating Lease, Liability, to be Paid, Year One Statement of Other Comprehensive Income [Abstract] Statement of Other Comprehensive Income [Abstract] Equity Awards Adjustments Equity Awards Adjustments [Member] Leasehold improvements Leasehold Improvements [Member] Other Other Noncash Income (Expense) Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Compensation Amount Outstanding Recovery Compensation Amount Dividend yield Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate Voting rights Common Stock, Voting Rights For Shareholders Common Stock, Voting Rights For Shareholders Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Collaboration revenue recognized from opening contract liability Contract with Customer, Liability, Revenue Recognized Research milestones payments received Research Milestones Payments Received Research milestones payments received. Deferred issuance costs recognized related to the "at the market" financing Deferred Issuance Costs Recognized Related To Equity Financing Deferred Issuance Costs Recognized Related To Equity Financing MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Name Awards Close in Time to MNPI Disclosures, Individual Name Weighted-average grant date fair value, beginning balance (in USD per share) Weighted-average grant date fair value, ending balance (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Restricted cash Restricted Cash, Noncurrent Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Shares available for issuance under employee stock purchase plan Employee Stock [Member] Additional payments Additional Payments Additional Payments ICFR Auditor Attestation Flag ICFR Auditor Attestation Flag Documents Incorporated by Reference Documents Incorporated by Reference [Text Block] Pre Funded Warrants Pre Funded Warrants [Member] Pre funded warrants. Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Accumulated other comprehensive income Accumulated Other Comprehensive Income (Loss), Net of Tax Aggregate intrinsic value, options vested and expected to vest as of November 30, 2024 Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Financial Instruments [Domain] Financial Instruments [Domain] Unrealized gain (loss) on available-for-sale marketable securities OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax License revenue License Revenue [Member] License Revenue Total deferred tax liabilities Deferred Tax Liabilities, Gross Auditor firm ID Auditor Firm ID Segments [Domain] Segments [Domain] Income Statement Location Statement of Income Location, Balance [Axis] Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Maintenance costs and real estate taxes Variable Lease, Payment Number of warrants (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Minimum Minimum [Member] Security deposit Security Deposit Less: Accumulated depreciation and amortization Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Net loss per share Earnings Per Share, Policy [Policy Text Block] Company Selected Measure Name Company Selected Measure Name Revenue Recognition Revenue [Policy Text Block] Preferred stock, $0.001 par value— 10,000,000 shares authorized as of November 30, 2025 and 2024; no shares issued and outstanding as of November 30, 2025 and 2024 Preferred Stock, Value, Issued Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Accounts payable Accounts Payable, Current Deferred tax liabilities: Deferred Tax Liabilities, Net [Abstract] Cash flows from operating leases Operating Lease, Payments Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] All Executive Categories All Executive Categories [Member] Schedule of Significant Components of Deferred Tax Assets for Federal and State Income Taxes Schedule of Deferred Tax Assets and Liabilities [Table Text Block] Common stock, $0.001 par value— 500,000,000 shares authorized as of November 30, 2025 and 2024; 101,807,484 and 75,870,718 shares issued and outstanding as of November 30, 2025 and 2024, respectively Common Stock, Value, Issued Expected volatility, minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Weighted-average number of shares outstanding, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Segments Segment Reporting, Policy [Policy Text Block] Commitments and contingencies (Note 6) Commitments and Contingencies Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Total provision for income taxes Current Federal, State and Local, Tax Expense (Benefit) Entity Small Business Entity Small Business Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Products arising from collaboration Number Of Products Arising From Collaboration Number Of Products Arising From Collaboration Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding State Current State and Local Tax Expense (Benefit) Document Transition Report Document Transition Report Options early exercised subject to vesting Option Early Exercised Subject To Vesting [Member] Option early exercised subject to vesting. Underlying Securities Award Underlying Securities Amount Net deferred tax assets Deferred Tax Assets, Net Additional drug targets Number Of Additional Specified Drug Targets Number Of Additional Specified Drug Targets Equity Component Equity Component [Domain] Document Period End Date Document Period End Date PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Income Taxes Income Tax Disclosure [Text Block] Balance Sheet Components Supplemental Balance Sheet Disclosures [Text Block] Brisbane, California Brisbane, California [Member] Brisbane, California Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Weighted-average contractual life, options exercisable as of November 30, 2024 (in years) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Schedule of Reconciliation of Beginning and Ending Amounts of Unrecognized Income Tax Benefits Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block] Operating lease liabilities Increase (Decrease) in Operating Lease Liability At The Market Financing At The Market Financing [Member] At The Market Financing Variable consideration included in transaction price Variable Consideration Included In Transaction Price Variable consideration included in transaction price. Defined Contribution Plan Defined Contribution Plan [Text Block] Document Type Document Type Gross Unrealized Loss Debt Securities, Available-for-Sale, Unrealized Loss Position [Abstract] Net Loss Per Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Product and Service [Axis] Product and Service [Axis] Unrealized loss, short-term Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax, Current Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax, Current Proceeds from issuances of common stock in "at the market" financing, net of issuance costs Proceeds from issuance of common stock Proceeds from Issuance of Common Stock Zelebrudomide (NX-2127) Zelebrudomide (NX-2127) [Member] Zelebrudomide (NX-2127) Total revenue Revenue from Contract with Customer, Excluding Assessed Tax Transfers of financial instruments Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers, Net Incentive Stock Option Incentive Stock Option [Member] Incentive stock option. All Individuals All Individuals [Member] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Options vested and expected to vest as of November 30, 2024 (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Name Forgone Recovery, Individual Name Award expiration period, years Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Total current assets Assets, Current Statistical Measurement Statistical Measurement [Axis] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Gilead Agreement Gilead Agreement [Member] Gilead agreement. Registered Direct Offerings Registered Direct Offerings [Member] Registered direct offerings. Non-statutory Stock Options and Options Granted to Consultants Non Statutory Stock Option And Options Granted To Consultants [Member] Non-statutory stock option and options granted to consultants. Number of drug candidates Number Of Drug Candidates Number Of Drug Candidates Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Percentage of fair value on grant date, percent Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent Total intrinsic value of stock options exercised Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value 2024 Equity Inducement Plan Two Thousand Twenty Four Equity Inducement Plan [Member] Two Thousand Twenty Four Equity Inducement Plan Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Current liabilities: Liabilities, Current [Abstract] Research and development tax credits Deferred Tax Assets, Tax Credit Carryforwards, Research Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] Geographical [Axis] Geographical [Axis] Transaction Type Transaction Type [Axis] Unrealized gain, short-term Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Current Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Current Total operating expenses Operating Expenses Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Risk-free interest rate, minimum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum Level 1 Fair Value, Inputs, Level 1 [Member] Beginning Balance (in shares) Ending Balance (in shares) Shares, Outstanding Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Warrant issuance costs Class of Warrant or Right, Offering Expenses Class of Warrant or Right, Offering Expenses Schedule Of Related Party Transactions By Related Party [Table] Related Party Transaction [Table] Net loss per share, diluted (in USD per share) Earnings Per Share, Diluted Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Title of 12(b) Security Title of 12(b) Security 2020 Employee Stock Purchase Plan ESPP Two Thousand Twenty Employee Stock Purchase Plan [Member] 2020 Employee stock purchase plan. Number of shares issued (in shares) Sale of Stock, Number of Shares Issued in Transaction Earnings Per Share [Abstract] Earnings Per Share [Abstract] Capitalized research and experimental expenses Deferred Tax Assets, Capitalized Research and Experimental Expenses Deferred Tax Assets, Capitalized Research and Experimental Expenses 2030 Lessee, Operating Lease, Liability, to be Paid, Year Five Accrued clinical Accrued Clinical, Current Accrued Clinical, Current Auditor location Auditor Location Schedule of Antidilutive Securities Excluded from Computation of Diluted Net Loss per Share of Common Stock Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Tax credit carryforwards Tax Credit Carryforward, Amount Minimum common stock holding percentage Minimum Common Stock Holding Percentage Minimum Common Stock Holding Percentage Deferred revenue Increase (Decrease) in Contract with Customer, Liability Comprehensive loss Comprehensive Income, Policy [Policy Text Block] Federal Domestic Tax Jurisdiction [Member] 2024 Public Offering Public Offering 2024 [Member] Public Offering 2024 Chief Financial Officer Chief Financial Officer [Member] Less: imputed interest Lessee, Operating Lease, Liability, Undiscounted Excess Amount Organization Consolidation And Presentation Of Financial Statements [Table] Organization Consolidation And Presentation Of Financial Statements [Table] Organization, consolidation and presentation of financial statements. Deferred offering costs Deferred Offering Costs Tax Credit Carryforward Tax Credit Carryforward [Axis] Accrued contract research and lab supplies Accrued Contract Research And Lab Supplies Accrued contract research and lab supplies. Contractual initial research period Contractual Initial Research Period Contractual initial research period. Upfront payment Upfront Payment Upfront payment. Weighted-average exercise price, options exercised (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Award Timing Disclosures [Line Items] Weighted-average exercise price, options granted (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Entity Well-known Seasoned Issuer Entity Well-known Seasoned Issuer Accrued compensation Employee-related Liabilities, Current Total operating lease liabilities Total undiscounted lease payments Lessee, Operating Lease, Liability, to be Paid Operating lease, renewal term Lessee, Operating Lease, Renewal Term Common Stock Equity [Text Block] Christine Ring [Member] Christine Ring Net loss Net loss Net Income (Loss) Attributable to Parent Subsequent Event [Table] Subsequent Event [Table] Schedule of Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Expiration Date Trading Arrangement Expiration Date Bexobrutideg (NX-5948) Bexobrutideg (NX-5948) [Member] Bexobrutideg (NX-5948) Expenses related to the healthcare plan premiums Related Party Transaction, Amounts of Transaction Schedule of Reconciliation of Statutory U.S. Federal Rate and Effective Rate Schedule of Effective Income Tax Rate Reconciliation [Table Text Block] Vesting period of options granted, years Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Other Effective Income Tax Rate Reconciliation, Other Adjustments, Percent Property and equipment, net Total property and equipment, net Property, Plant and Equipment, Net Collaboration agreement contract term Collaboration Agreement Contract Term Collaboration agreement contract term. Segment Reporting Information [Line Items] Segment Reporting Information [Line Items] Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Numerator: Net Income (Loss) Attributable to Parent [Abstract] Adoption Date Trading Arrangement Adoption Date Issuance of Series D redeemable convertible preferred stock, per share (in USD per share) Shares Issued, Price Per Share Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Contract assets Contract with Customer, Asset, after Allowance for Credit Loss Proceeds from issuance of common stock under employee stock purchase plan Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised Entity Current Reporting Status Entity Current Reporting Status Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Loss from operations Operating Income (Loss) Accumulated deficit Retained Earnings (Accumulated Deficit) Vesting of restricted stock units (in shares) Restricted Stock, Shares Issued Net of Shares for Tax Withholdings Transaction Transaction [Domain] Financial Instrument [Axis] Financial Instrument [Axis] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Executive Category: Executive Category [Axis] Pfizer Pfizer [Member] Pfizer Greater than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Vesting of early exercised stock options Adjustments To Additional Paid In Capital Share Based Compensation Vesting Of Early Exercised Stock Options Adjustments to additional paid in capital share based compensation vesting of early exercised stock options. State income tax rate Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent Current Fiscal Year End Date Current Fiscal Year End Date Expected term (years) Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term Less than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Subsequent Event Type [Domain] Subsequent Event Type [Domain] Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Weighted-average grant date fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Statement [Table] Statement [Table] Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Collaboration Agreements Collaborative Arrangement Disclosure [Text Block] Cash flows from financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Weighted-average grant date fair value of options granted (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Total Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Additional payment received to exercise option to expand number of targets Additional Payment Received To Exercise Option To Expand Number Of Targets Additional payment received to exercise option to expand number of targets. Recorded deferred revenue Contract with Customer, Liability Schedule of Accrued Expenses and Other Current Liabilities Schedule Of Accrued Expenses And Other Liabilities [Table Text Block] Schedule of expenses accrued and other liabilities. Unrecognized tax benefits Balance at beginning of period Balance at end of period Unrecognized Tax Benefits Anti-dilutive securities excluded from computation of diluted net loss per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Denominator: Weighted Average Number of Shares Outstanding, Diluted [Abstract] All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Sale price of stock (in USD per share) Sale of Stock, Price Per Share Other Commitments [Table] Other Commitments [Table] Termination Date Trading Arrangement Termination Date Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Measure: Measure [Axis] Operating lease, weighted average discount rate, percent Operating Lease, Weighted Average Discount Rate, Percent Schedule of Option Activity under the Stock Plans Share-Based Payment Arrangement, Option, Activity [Table Text Block] Research and development milestone payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Research And Development Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Research And Development Milestones Long-Lived Tangible Asset Long-Lived Tangible Asset [Domain] Schedule of Investments Fair Value Measurement on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Weighted-average number of shares outstanding, basic (in shares) Weighted Average Number of Shares Outstanding, Basic Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Unrecognized tax benefits that would impact effective tax rate Unrecognized Tax Benefits that Would Impact Effective Tax Rate Schedule of Computation of Basic and Diluted Net Loss per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Deferred issuance costs included in accounts payable and accrued expenses and other current liabilities Deferred Issuance Costs Included In Accounts Payable And Accrued Expenses And Other Liabilities Deferred Issuance Costs Included In Accrued Expenses And Other Liabilities Related Party Transaction [Domain] Related Party Transaction [Domain] Options exercisable as of November 30, 2024 (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number Subsequent Events [Abstract] Segment Reporting [Abstract] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Operating lease expenses, excluding variable lease payments Operating Lease, Expense Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Entity Tax Identification Number Entity Tax Identification Number Weighted-average price per share (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased Weighted-average exercise price, beginning balance (in USD per share) Weighted-average exercise price, ending balance (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Common stock, par value (in USD per share) Common Stock, Par or Stated Value Per Share Common stock, shares issued (in shares) Common Stock, Shares, Issued Summary Of Significant Accounting Policies [Line Items] Summary Of Significant Accounting Policies [Line Items] Summary of significant accounting policies. Operating lease right-of-use assets Deferred Tax Liabilities Operating Lease Right Of Use Assets Deferred tax liabilities operating lease right-of-use assets. Operating lease, weighted average remaining lease term Operating Lease, Weighted Average Remaining Lease Term Warrants offering expenses Warrants Offering Expenses Warrants Offering Expenses Number of performance obligations Number Of Performance Obligations Number Of Performance Obligations Number of options outstanding, options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Current: Current Federal, State and Local, Tax Expense (Benefit) [Abstract] Use of Estimates Use of Estimates, Policy [Policy Text Block] Entity Public Float Entity Public Float Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block] Trading Arrangement: Trading Arrangement [Axis] Total Shareholder Return Amount Total Shareholder Return Amount Subsequent Events Subsequent Events [Text Block] Insider Trading Arrangements [Line Items] Proceeds from issuances of common stock and pre-funded warrants, net of issuance costs Proceeds from Issuance of Warrants Security Exchange Name Security Exchange Name Weighted-average exercise price, options forfeited (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Tenant Improvements Tenant Improvements Allowance for credit losses Debt Securities, Available-for-Sale, Allowance for Credit Loss, Excluding Accrued Interest Maximum increase or decrease percentage of warrants Maximum Increase Or Decrease Percentage Of Warrants Maximum Increase Or Decrease Percentage Of Warrants Total liabilities Liabilities Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Purchase price of warrants (in USD per share) Class Of Warrant Or Right, Purchase Price Of Warrants Or Rights Class Of Warrant Or Right, Purchase Price Of Warrants Or Rights Additions to property and equipment included in accounts payable and accrued expenses and other current liabilities Capital Expenditures Incurred but Not yet Paid Other Risks and Uncertainties Other Risks And Uncertainties Policy Policy [Policy Text Block] Other risks and uncertainties policy. At the Market Offering At The Market Offerings [Member] At the market offerings. Marketable securities Estimated fair value, short-term Debt Securities, Available-for-Sale, Excluding Accrued Interest, Current Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Additions based on tax positions related to current period Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions Repurchase of unvested early exercised stock (in shares) Stock Repurchased During Period, Shares Operating expenses: Operating Expenses [Abstract] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Other Other Liabilities, Current Revenue recognized Contract With Customer Liability Revenue Recognized Excluding Opening Balance Contract With Customer Liability Revenue Recognized Excluding Opening Balance Issuance of common stock and pre-funded warrants, net of issuance costs Stock Issued During Period, Value, New Issues Accrued expenses and other liabilities Deferred Tax Assets Accrued Expenses And Other Liabilities Deferred tax assets accrued expenses and other liabilities. Statement [Line Items] Statement [Line Items] Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Cash and cash equivalents Cash and Cash Equivalent Counterparty Name Counterparty Name [Axis] Schedule of RSU Activity Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Subsequent Event [Line Items] Subsequent Event [Line Items] Research Research Tax Credit Carryforward [Member] Risk-free interest rate, maximum Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum Common stock Common Stock [Member] RSUs vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Tax Credit Carryforward, Name Tax Credit Carryforward, Name [Domain] Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Non-NEOs Non-NEOs [Member] Net increase (decrease) in cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Healthcare Plan Provider Trust for Benefit of Employees [Member] Valuation allowance offsetting unrecognized tax benefits Deferred Tax Assets, Valuation Allowance, Offset To Unrecognized Tax Benefits Deferred Tax Assets, Valuation Allowance, Offset To Unrecognized Tax Benefits Accrued professional services Accrued Professional Fees, Current