Summary of Significant Accounting Policies Significant Accounting Policies [Text Block] Statistical Measurement Statistical Measurement [Domain] Award Timing Predetermined Award Timing Predetermined [Flag] Related Party Transaction [Axis] Related Party Transaction [Axis] Entity File Number Entity File Number Additional paid-in capital Additional Paid-in Capital Additional Paid-in Capital [Member] Performance obligation satisfied Contract with Customer, Performance Obligation Satisfied in Previous Period Tabular List, Table Tabular List [Table Text Block] Recently Adopted Accounting Pronouncements Not Yet adopted New Accounting Pronouncements, Policy [Policy Text Block] Regulatory milestone payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Regulatory Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Regulatory Milestones Fair Value Measurements Fair Value Measurement and Measurement Inputs, Recurring and Nonrecurring [Text Block] Accounts payable Increase (Decrease) in Accounts Payable Impairment losses related to marketable securities Impairment Loss On Marketable Securities Impairment loss on marketable securities. Shares available for future equity grants Share-Based Payment Arrangement [Member] Unrealized loss Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Trading Arrangements, by Individual Trading Arrangements, by Individual [Table] Software in progress Software In Progress [Member] Software in progress. Net loss per share, basic (in USD per share) Earnings Per Share, Basic Adjustment to Compensation: Adjustment to Compensation [Axis] Related Party Transactions Related Party Transactions Disclosure [Text Block] Named Executive Officers, Footnote Named Executive Officers, Footnote [Text Block] Total common stock reserved for future issuance (in shares) Common Stock, Capital Shares Reserved for Future Issuance Target licensing and reservation payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Target Licensing And Reservation Revenue, Remaining Performance Obligation, Variable Consideration Amount, Target Licensing And Reservation Schedule Of Stock By Class [Table] Stock, Class of Stock [Table] Equity Distribution Agreement Equity Distribution Agreement [Member] Equity distribution agreement. Issuance of common stock under employee stock purchase plan (in shares) Stock Issued During Period, Shares, Employee Stock Purchase Plans Equity distribution agreement, commission percentage on gross sales price of shares Commission Percentage On Gross Sales Price Of Shares Commission percentage on gross sales price of shares. Adjustment to Compensation, Amount Adjustment to Compensation Amount Transfer of financial instruments between valuation levels Transfers Of Financial Instruments Between Valuation Levels Transfers of financial instruments between valuation levels. Stock-based compensation Share-Based Payment Arrangement, Noncash Expense Options to purchase common stock issued and outstanding Employee Stock Option Options to purchase common stock issued and outstanding Share-Based Payment Arrangement, Option [Member] Award Timing MNPI Disclosure Award Timing MNPI Disclosure [Text Block] Schedule Of Property Plant And Equipment [Table] Property, Plant and Equipment [Table] Included in cash and cash equivalents Cash and Cash Equivalents [Member] Antidilutive Securities Antidilutive Securities [Axis] Total stockholdersʼ equity Beginning balance Ending balance Equity, Attributable to Parent Measurement Frequency Measurement Frequency [Axis] Other comprehensive income (loss), net of tax: Other Comprehensive Income (Loss), Net of Tax [Abstract] Insider Trading Policies and Procedures [Line Items] Total stock-based compensation Share-Based Payment Arrangement, Expense Schedule of Property and Equipment Property, Plant and Equipment [Table Text Block] Common stock, shares authorized (in shares) Common stock, shares authorized to issue (in shares) Common Stock, Shares Authorized Issuance of common stock and pre-funded warrants in connection with equity financing, net of issuance costs (in shares) Issuance of common stock and pre-funded warrants, net of issuance costs (in shares) Stock Issued During Period, Shares, New Issues Current assets: Assets, Current [Abstract] Options forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period Total liabilities and stockholdersʼ equity Liabilities and Equity Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Fair Value Measurements, Recurring Fair Value, Recurring [Member] Extension payment Proceeds From Collaboration Agreement, Extension Payment Proceeds From Collaboration Agreement, Extension Payment Number of options outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Concentration of Credit Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Liabilities and stockholdersʼ equity Liabilities and Equity [Abstract] Cover [Abstract] Cover [Abstract] Maximum Maximum [Member] General and administrative General and Administrative Expense [Member] Accounting Policies [Abstract] Accounting Policies [Abstract] Total Debt Securities, Available-for-Sale, Unrealized Loss Position Restricted stock units issued and outstanding Restricted Stock [Member] Non-PEO NEO Average Total Compensation Amount Non-PEO NEO Average Total Compensation Amount Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Adjustment to Non-PEO NEO Compensation Footnote Adjustment to Non-PEO NEO Compensation Footnote [Text Block] Pay vs Performance Disclosure [Line Items] Class of Warrant or Right Class of Warrant or Right [Axis] Operating lease, liability Operating Lease, Liability U.S. government agency securities US Government Agencies Debt Securities [Member] Term extension Collaboration Agreement Contract Term, Extension Collaboration Agreement Contract Term, Extension Retirement Benefits [Abstract] Retirement Benefits [Abstract] Forgone Recovery due to Disqualification of Tax Benefits, Amount Forgone Recovery due to Disqualification of Tax Benefits, Amount Non-Rule 10b5-1 Arrangement Terminated Non-Rule 10b5-1 Arrangement Terminated [Flag] Depreciation and amortization Depreciation, Depletion and Amortization, Nonproduction Loss before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Entity Shell Company Entity Shell Company Statement of Stockholders' Equity [Abstract] Statement of Stockholders' Equity [Abstract] Accrued expenses and other current liabilities Increase (Decrease) in Other Accounts Payable and Accrued Liabilities Drug targets Number Of Specified Drug Targets Number Of Specified Drug Targets Statement of Cash Flows [Abstract] Statement of Cash Flows [Abstract] Company Selected Measure Amount Company Selected Measure Amount Award Timing MNPI Considered Award Timing MNPI Considered [Flag] Total comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Issuance of pre funded warrants Stock Issued During Period, Value, New Issues And Adjustments To Additional Paid In Capital, Warrant Issued Stock Issued During Period, Value, New Issues And Adjustments To Additional Paid In Capital, Warrant Issued Name Measure Name Upfront payment of additional fees Upfront Payment Of Additional Fees Upfront payment of additional fees. Schedule of Stock-Based Compensation Expense Related to Stock Options and 2020 ESPP Included in Statements of Operations Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Operating lease liabilities, current Operating Lease, Liability, Current Class Of Stock [Line Items] Class of Stock [Line Items] Software Software and Software Development Costs [Member] Document Fiscal Period Focus Document Fiscal Period Focus Award Timing Method Award Timing Method [Text Block] Amortized cost Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss Furniture and fixtures Furniture and Fixtures [Member] Award Type Award Type [Axis] Deferred revenue, net of current portion Contract with Customer, Liability, Noncurrent Total assets Assets Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Trading Symbol Trading Symbol Weighted-average grant date fair value, RSUs vested (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value Geographical [Domain] Geographical [Domain] Entity Address, City or Town Entity Address, City or Town Cash flows from operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Organization Organization, Consolidation and Presentation of Financial Statements Disclosure and Significant Accounting Policies [Text Block] Cash paid for amounts included in the measurement of lease liabilities: Additional Cash Flow Elements and Supplemental Cash Flow Information [Abstract] Non-PEO NEO Average Compensation Actually Paid Amount Non-PEO NEO Average Compensation Actually Paid Amount Income Statement Location Statement of Income Location, Balance [Domain] Restricted stock units issued and outstanding Restricted Stock Units (RSUs) Restricted Stock Units (RSUs) [Member] Reconciliation of cash, cash equivalents and restricted cash: Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Including Discontinued Operation [Abstract] Compensation Actually Paid vs. Other Measure Compensation Actually Paid vs. Other Measure [Text Block] Number of renewal options Lessee, Operating Lease, Number Of Renewal Options Lessee, Operating Lease, Number Of Renewal Options Entity Emerging Growth Company Entity Emerging Growth Company Common stock, dividends declared (in USD per share) Common Stock, Dividends, Per Share, Declared Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Right-of-use assets recognized in exchange for lease obligations Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Options outstanding, beginning balance (in shares) Options outstanding, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year [Member] Expiration term Collaboration Agreement Expiration Term Collaboration Agreement Expiration Term Level 2 Fair Value, Inputs, Level 2 [Member] Deferred issuance costs included in accrued expenses and other current liabilities Deferred Issuance Costs Included In Accrued Expenses And Other Liabilities Deferred Issuance Costs Included In Accrued Expenses And Other Liabilities Insider Trading Policies and Procedures Not Adopted Insider Trading Policies and Procedures Not Adopted [Text Block] Common stock, shares outstanding (in shares) Common Stock, Shares, Outstanding Plan Name Plan Name [Axis] PEO PEO [Member] Supplemental disclosures of non-cash investing and financing activities: Noncash Investing and Financing Items [Abstract] Shares issued (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Shares Issued in Period Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Exercise of stock options Stock Issued During Period, Value, Stock Options Exercised Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year Dividends or Other Earnings Paid on Equity Awards not Otherwise Reflected in Total Compensation for Covered Year [Member] Accumulated deficit Retained Earnings [Member] Accrued expenses and other current liabilities Accrued Expenses And Other Liabilities Current Accrued expenses and other liabilities current. Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Entity Address, Postal Zip Code Entity Address, Postal Zip Code Restatement Determination Date Restatement Determination Date Share-Based Payment Arrangement [Abstract] Share-Based Payment Arrangement [Abstract] Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Total cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Income Statement [Abstract] Income Statement [Abstract] Provision for income taxes Current income tax expenses or provision Income Tax Expense (Benefit) Greater than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer Clinical milestone payment Proceeds From Collaboration Agreement, Clinical Milestone Payment Proceeds From Collaboration Agreement, Clinical Milestone Payment Purchases of marketable securities Payments to Acquire Marketable Securities Sale of Stock Sale of Stock [Domain] Accrued taxes Taxes Payable, Current Preferred stock, shares issued (in shares) Preferred Stock, Shares Issued Pension Adjustments Service Cost Pension Adjustments Service Cost [Member] Product and Service [Domain] Product and Service [Domain] Fair Value Debt Securities, Available-for-Sale [Abstract] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Axis] Rent payable per month Operating Lease Rent Payable Adjustment, Per Month Operating lease rent payable per month. Total property and equipment, gross Property, Plant and Equipment, Gross Cash and short-term investments Cash, Cash Equivalents, and Short-Term Investments Restatement does not require Recovery Restatement Does Not Require Recovery [Text Block] Proceeds from issuances of common stock and pre-funded warrants in equity financing, net of issuance costs Proceeds From Issuance Of Common Stock And Warrants Proceeds From Issuance Of Common Stock And Warrants Organization, Consolidation and Presentation of Financial Statements [Abstract] Organization, Consolidation and Presentation of Financial Statements [Abstract] Amortization of operating lease right-of-use assets Operating Lease, Right-of-Use Asset, Periodic Reduction Compensation Actually Paid vs. Company Selected Measure Compensation Actually Paid vs. Company Selected Measure [Text Block] Proceeds from exercise of stock options Proceeds from Stock Options Exercised City Area Code City Area Code Award Timing, How MNPI Considered Award Timing, How MNPI Considered [Text Block] All Trading Arrangements All Trading Arrangements [Member] Equity Awards Adjustments, Footnote Equity Awards Adjustments, Footnote [Text Block] Total Shareholder Return Vs Peer Group Total Shareholder Return Vs Peer Group [Text Block] Schedule of Accrued Expenses and Other Current Liabilities Schedule Of Accrued Expenses And Other Current Liabilities Table [Table Text Block] Schedule of accrued expenses and other current liabilities. Number of RSUs, beginning balance (in shares) Number of RSUs, ending balance (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Commitments and Contingencies Disclosure [Abstract] Commitments and Contingencies Disclosure [Abstract] Cash flows from investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] General and administrative General and Administrative Expense Total compensation cost related to stock-based awards yet to recognize Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Pay vs Performance Disclosure Pay vs Performance Disclosure [Table] Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Related Party Transactions [Abstract] Related Party Transactions [Abstract] Estimated fair value Debt Securities, Available-for-Sale, Excluding Accrued Interest Preferred stock, par value (in USD per share) Preferred Stock, Par or Stated Value Per Share Equity Valuation Assumption Difference, Footnote Equity Valuation Assumption Difference, Footnote [Text Block] Schedule of Other Information Related to Leases Lease, Cost [Table Text Block] PEO Total Compensation Amount PEO Total Compensation Amount Prepaid Expenses and Other Current Assets Prepaid Expenses and Other Current Assets [Member] Money market funds Money Market Funds [Member] Equity Components Equity Components [Axis] Property, Plant and Equipment [Line Items] Property, Plant and Equipment [Line Items] Non-Rule 10b5-1 Arrangement Adopted Non-Rule 10b5-1 Arrangement Adopted [Flag] Interest and other income, net Interest and Other Income Other Performance Measure, Amount Other Performance Measure, Amount Weighted- average exercise price Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract] Entity Address, State or Province Entity Address, State or Province Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Antidilutive Security, Excluded EPS Calculation [Table] Related Party Related and Nonrelated Parties [Domain] Total current liabilities Liabilities, Current Area of office space leased Area Of Office Space Leased Area of office space leased. Underwriters Over-Allotment Option [Member] Individual: Individual [Axis] Organization Consolidation And Presentation Of Financial Statements [Line Items] Organization Consolidation And Presentation Of Financial Statements [Line Items] Organization, consolidation and presentation of financial statements. Contribution expense Defined Contribution Plan, Cost Research and development Research and Development Expense [Member] Additional paid-in capital Additional Paid in Capital, Common Stock Net cash provided by (used in) investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table Aggregate Change in Present Value of Accumulated Benefit for All Pension Plans Reported in Summary Compensation Table [Member] Document Fiscal Year Focus Document Fiscal Year Focus Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Operating lease right-of-use assets Operating Lease, Right-of-Use Asset Forgone Recovery, Explanation of Impracticability Forgone Recovery, Explanation of Impracticability [Text Block] Entity Interactive Data Current Entity Interactive Data Current Plan Name Plan Name [Domain] Total compensation cost related to stock-based awards, recognition period Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Exercise of stock options (in shares) Options exercised (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Revenue Recognition Revenue from Contract with Customer [Policy Text Block] Piper Sandler & Co. Piper Sandler And Co [Member] Piper Sandler & Co. Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items] Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items] U.S. treasury securities US Treasury Securities [Member] Certain sales milestones payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Certain Sales Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Certain Sales Milestones Long-Lived Tangible Asset Long-Lived Tangible Asset [Axis] Other Commitments [Line Items] Other Commitments [Line Items] Increase (Decrease) in Stockholders' Equity [Roll Forward] Increase (Decrease) in Stockholders' Equity [Roll Forward] Extended research term Contractual Extended Research Period Contractual extended research period. Compensation Actually Paid vs. Total Shareholder Return Compensation Actually Paid vs. Total Shareholder Return [Text Block] Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table] Fair Value, Recurring and Nonrecurring [Table] Leases Lessee, Leases [Policy Text Block] Other assets Other Assets, Noncurrent Entity Central Index Key Entity Central Index Key PEO Name PEO Name Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year [Member] Outstanding Aggregate Erroneous Compensation Amount Outstanding Aggregate Erroneous Compensation Amount Arrangement Duration Trading Arrangement Duration Computer equipment Computer Equipment [Member] Deferred revenue, current Contract with Customer, Liability, Current Exercise price of warrants (in USD per share) Class of Warrant or Right, Exercise Price of Warrants or Rights Prepaid expenses and other assets Increase (Decrease) in Prepaid Expense and Other Assets Exercise Price Award Exercise Price Entity Filer Category Entity Filer Category Local Phone Number Local Phone Number Additional 402(v) Disclosure Additional 402(v) Disclosure [Text Block] Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Domain] Stock-Based Compensation Share-Based Payment Arrangement [Text Block] Assets Assets [Abstract] Total accrued expenses and other current liabilities Accrued And Other Liabilities Current Accrued and other liabilities current. Underlying Security Market Price Change Underlying Security Market Price Change, Percent Balance Sheet Location Statement of Financial Position Location, Balance [Axis] Amortized cost, short-term Debt Securities, Available-for-Sale, Amortized Cost, Excluding Accrued Interest, after Allowance for Credit Loss, Current Class of Warrant or Right Class of Warrant or Right [Domain] Debt Instrument [Axis] Debt Instrument [Axis] Laboratory equipment Laboratory Equipment [Member] Laboratory equipment. Weighted-average grant date fair value, RSUs forfeited (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Stockholdersʼ equity: Equity, Attributable to Parent [Abstract] Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year [Member] Entity Address, Address Line One Entity Address, Address Line One Entity Address, Address Line Two Entity Address, Address Line Two Third Amendment Third Amendment [Member] Third Amendment Research and development Research and Development Expense Accumulated other comprehensive income (loss) AOCI Attributable to Parent [Member] Operating lease liabilities, net of current portion Operating Lease, Liability, Noncurrent Balance Sheet Related Disclosures [Abstract] Balance Sheet Related Disclosures [Abstract] Repurchase of unvested early exercised stock options Payments For Repurchase Of Stock Options Payments For Repurchase Of Stock Options Fair Value as of Grant Date Award Grant Date Fair Value Accounts receivable Accounts Receivable, after Allowance for Credit Loss Entity Registrant Name Entity Registrant Name Stock Price or TSR Estimation Method Stock Price or TSR Estimation Method [Text Block] Equity Incentive Plans Equity Incentive Plans [Member] Equity Incentive Plans Collaboration revenue Collaboration Revenue [Member] Collaboration Revenue RSUs granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Vesting of early exercised stock options Vesting Of Early Exercised Stock Options Vesting of early exercised stock options. RSUs forfeited (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Related Party Transaction [Line Items] Related Party Transaction [Line Items] Document Quarterly Report Document Quarterly Report Less than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Issuance of common stock and pre-funded warrants in connection with equity financing, net of issuance costs Issuance costs, common stock Adjustments to Additional Paid in Capital, Stock Issued, Issuance Costs Changed Peer Group, Footnote Changed Peer Group, Footnote [Text Block] Accrued interest receivable Interest Receivable, Current Counterparty Name Counterparty Name [Domain] Net accretion of discount on marketable securities Accretion (Amortization) of Discounts and Premiums, Investments Adjustment To PEO Compensation, Footnote Adjustment To PEO Compensation, Footnote [Text Block] Related Party Related and Nonrelated Parties [Axis] Weighted-average grant date fair value, RSUs granted (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Title Trading Arrangement, Individual Title Peer Group Total Shareholder Return Amount Peer Group Total Shareholder Return Amount Collaborative Arrangement and Arrangement Other than Collaborative Collaborative Arrangement and Arrangement Other than Collaborative [Axis] Restatement Determination Date: Restatement Determination Date [Axis] Non-PEO NEO Non-PEO NEO [Member] Issuance of common stock under employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan Stock Plans and ESPP Stock Plans And Employee Stock Purchase Plan [Member] Stock plans and employee stock purchase plan. Sale of Stock Sale of Stock [Axis] Unrealized gain Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Name Trading Arrangement, Individual Name Award Type Award Type [Domain] Sanofi Agreement Sanofi Agreement [Member] Sanofi agreement. Statement of Other Comprehensive Income [Abstract] Statement of Other Comprehensive Income [Abstract] Equity Awards Adjustments Equity Awards Adjustments [Member] Leasehold improvements Leasehold Improvements [Member] Pension Benefits Adjustments, Footnote Pension Benefits Adjustments, Footnote [Text Block] Compensation Amount Outstanding Recovery Compensation Amount Debt Instrument, Name [Domain] Debt Instrument, Name [Domain] Voting rights Common Stock, Voting Rights For Shareholders Common Stock, Voting Rights For Shareholders Schedule of Common Stock Shares Reserved for Future Issuance Schedule Of Common Stock Shares Reserved For Future Issuance Table [Table Text Block] Schedule of common stock shares reserved for future issuance. Recovery of Erroneously Awarded Compensation Disclosure [Line Items] Collaboration revenue recognized from opening contract liability Contract with Customer, Liability, Revenue Recognized Research milestones payments received Research Milestones Payments Received Research milestones payments received. Deferred issuance costs recognized related to the “at the market” financing Deferred Issuance Costs Recognized Related To Equity Financing Deferred Issuance Costs Recognized Related To Equity Financing MNPI Disclosure Timed for Compensation Value MNPI Disclosure Timed for Compensation Value [Flag] Name Awards Close in Time to MNPI Disclosures, Individual Name Weighted-average grant date fair value, beginning balance (in USD per share) Weighted-average grant date fair value, ending balance (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Restricted cash Restricted cash Restricted Cash, Noncurrent Aggregate Erroneous Compensation Not Yet Determined Aggregate Erroneous Compensation Not Yet Determined [Text Block] Shares available for issuance under employee stock purchase plan Employee Stock Shares expected to be purchased under employee stock purchase plan Employee Stock [Member] Additional payments Additional Payments Additional Payments Pre Funded Warrants Pre-funded warrants issued and outstanding Pre Funded Warrants [Member] Pre funded warrants. Debt securities unrealized loss position, more than12 months number of positions Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Number of Positions Stock-based compensation APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Accumulated other comprehensive income (loss) Accumulated Other Comprehensive Income (Loss), Net of Tax Financial Instruments Financial Instruments [Domain] Unrealized gain (loss) on available-for-sale marketable securities OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax License revenue License Revenue [Member] License Revenue Income Statement Location Statement of Income Location, Balance [Axis] Aggregate Pension Adjustments Service Cost Aggregate Pension Adjustments Service Cost [Member] Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Maintenance costs and real estate taxes Variable Lease, Payment Balance Sheet Location Statement of Financial Position Location, Balance [Domain] Number of warrants (in shares) Class of Warrant or Right, Number of Securities Called by Warrants or Rights Minimum Minimum [Member] Security deposit Security Deposit Less: Accumulated depreciation and amortization Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment Company Selected Measure Name Company Selected Measure Name Preferred stock, $0.001 par value— 10,000,000 shares authorized as of May 31, 2025 and November 30, 2024; no shares issued and outstanding as of May 31, 2025 and November 30, 2024 Preferred Stock, Value, Issued Aggregate Available Trading Arrangement, Securities Aggregate Available Amount Accounts payable Accounts Payable, Current Cash flows from operating leases Operating Lease, Payments Stock Appreciation Rights (SARs) Stock Appreciation Rights (SARs) [Member] All Executive Categories All Executive Categories [Member] Common stock, $0.001 par value— 500,000,000 shares authorized as of May 31, 2025 and November 30, 2024; 76,433,664 and 75,870,718 shares issued and outstanding as of May 31, 2025 and November 30, 2024, respectively Common Stock, Value, Issued Commitments and Contingencies Commitments and Contingencies Disclosure [Text Block] Weighted-average number of shares outstanding, diluted (in shares) Weighted Average Number of Shares Outstanding, Diluted Commitments and contingencies (Note 6) Commitments and Contingencies Non-GAAP Measure Description Non-GAAP Measure Description [Text Block] Entity Small Business Entity Small Business Income Tax Disclosure [Abstract] Income Tax Disclosure [Abstract] Products arising from collaboration Number Of Products Arising From Collaboration Number Of Products Arising From Collaboration Preferred stock, shares outstanding (in shares) Preferred Stock, Shares Outstanding Document Transition Report Document Transition Report Underlying Securities Award Underlying Securities Amount Additional drug targets Number Of Additional Specified Drug Targets Number Of Additional Specified Drug Targets Equity Component Equity Component [Domain] Document Period End Date Document Period End Date PEO Actually Paid Compensation Amount PEO Actually Paid Compensation Amount Income Taxes Income Tax Disclosure [Text Block] Condensed Balance Sheet Components Supplemental Balance Sheet Disclosures [Text Block] Brisbane, California Brisbane, California [Member] Brisbane, California Awards Close in Time to MNPI Disclosures, Table Awards Close in Time to MNPI Disclosures [Table Text Block] Operating lease liabilities Increase (Decrease) in Operating Lease Liability At The Market Financing At The Market Financing [Member] At The Market Financing Variable consideration included in transaction price Variable Consideration Included In Transaction Price Variable consideration included in transaction price. Defined Contribution Plan Defined Contribution Plan [Text Block] Other Risks and Uncertainties Other Risks And Uncertainties [Policy Text Block] Other risks and uncertainties policy. Document Type Document Type Gross Unrealized Loss Debt Securities, Available-for-Sale, Unrealized Loss Position [Abstract] Net Loss Per Share Earnings Per Share [Text Block] Name Outstanding Recovery, Individual Name Product and Service [Axis] Product and Service [Axis] Unrealized loss, short-term Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax, Current Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax, Current Proceeds from issuances of common stock in “at the market” financing, net of issuance costs Proceeds from issuance of common stock Proceeds from Issuance of Common Stock Total revenue Revenue Revenue from Contract with Customer, Excluding Assessed Tax All Individuals All Individuals [Member] Fair Value Disclosures [Abstract] Fair Value Disclosures [Abstract] Purchases of property and equipment Payments to Acquire Property, Plant, and Equipment Name Forgone Recovery, Individual Name Total current assets Assets, Current Statistical Measurement Statistical Measurement [Axis] Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested [Member] Gilead Agreement Gilead Agreement [Member] Gilead agreement. Registered Direct Offerings Registered Direct Offerings [Member] Registered direct offerings. Remaining stock available for sale Sale Of Stock, Common Stock Remaining Available For Sale Sale Of Stock, Common Stock Remaining Available For Sale Number of drug candidates Number Of Drug Candidates Number Of Drug Candidates Aggregate Erroneous Compensation Amount Aggregate Erroneous Compensation Amount Two Thousand Twenty Four Equity Inducement Plan Two Thousand Twenty Four Equity Inducement Plan [Member] Two Thousand Twenty Four Equity Inducement Plan Peer Group Issuers, Footnote Peer Group Issuers, Footnote [Text Block] Erroneous Compensation Analysis Erroneous Compensation Analysis [Text Block] Current liabilities: Liabilities, Current [Abstract] Geographical [Axis] Geographical [Axis] Transaction Type Transaction Type [Axis] Unrealized gain, short-term Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Current Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax, Current Total operating expenses Operating Expenses Rule 10b5-1 Arrangement Terminated Rule 10b5-1 Arrangement Terminated [Flag] Level 1 Fair Value, Inputs, Level 1 [Member] Beginning balance (in shares) Ending balance (in shares) Shares, Outstanding Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Schedule Of Related Party Transactions By Related Party [Table] Related Party Transaction [Table] Net loss per share, diluted (in USD per share) Earnings Per Share, Diluted Erroneously Awarded Compensation Recovery Erroneously Awarded Compensation Recovery [Table] Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current Title of 12(b) Security Title of 12(b) Security Number of shares issued (in shares) Sale of Stock, Number of Shares Issued in Transaction Earnings Per Share [Abstract] Earnings Per Share [Abstract] Accrued clinical Accrued Clinical, Current Accrued Clinical, Current Schedule of Antidilutive Securities Excluded from Computation of Diluted Net Loss per Share of Common Stock Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Minimum common stock holding percentage Minimum Common Stock Holding Percentage Minimum common stock holding percentage. Deferred revenue Increase (Decrease) in Contract with Customer, Liability 2024 Public Offering Public Offering 2024 [Member] Public Offering 2024 Chief Financial Officer Chief Financial Officer [Member] Organization Consolidation And Presentation Of Financial Statements [Table] Organization Consolidation And Presentation Of Financial Statements [Table] Organization, consolidation and presentation of financial statements. Accrued contract research and lab supplies Accrued Contract Research And Lab Supplies Accrued contract research and lab supplies. Contractual initial research period Contractual Initial Research Period Contractual initial research period. Upfront payment Upfront Payment Upfront payment. Weighted-average exercise price, options exercised (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Award Timing Disclosures [Line Items] Weighted-average exercise price, options granted (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Measurement Frequency Measurement Frequency [Domain] Accrued compensation Employee-related Liabilities, Current Future minimum lease payments Lessee, Operating Lease, Liability, to be Paid Renewal term Lessee, Operating Lease, Renewal Term Common Stock Equity [Text Block] Net loss Net loss Net loss Net Income (Loss) Attributable to Parent Schedule of Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block] Expiration Date Trading Arrangement Expiration Date Expenses related to the healthcare plan premiums Related Party Transaction, Amounts of Transaction Property and equipment, net Total property and equipment, net Property, Plant and Equipment, Net Collaboration agreement contract term Collaboration Agreement Contract Term Collaboration agreement contract term. Preferred stock, shares authorized (in shares) Preferred Stock, Shares Authorized Numerator: Net Income (Loss) Attributable to Parent [Abstract] Adoption Date Trading Arrangement Adoption Date Issuance of Series D redeemable convertible preferred stock, per share (in USD per share) Shares Issued, Price Per Share Compensation Actually Paid vs. Net Income Compensation Actually Paid vs. Net Income [Text Block] Accounts receivable Increase (Decrease) in Accounts Receivable Contract assets Contract with Customer, Asset, after Allowance for Credit Loss Proceeds from issuance of common stock under employee stock purchase plan Proceeds, Issuance of Shares, Share-Based Payment Arrangement, Excluding Option Exercised Entity Current Reporting Status Entity Current Reporting Status Awards Close in Time to MNPI Disclosures Awards Close in Time to MNPI Disclosures [Table] Loss from operations Operating Income (Loss) Accumulated deficit Retained Earnings (Accumulated Deficit) Vesting of restricted stock units (in shares) Restricted Stock, Shares Issued Net of Shares for Tax Withholdings Transaction Transaction [Domain] Financial Instrument Financial Instrument [Axis] Statement of Financial Position [Abstract] Statement of Financial Position [Abstract] Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested [Member] Executive Category: Executive Category [Axis] Pfizer Pfizer [Member] Pfizer Greater than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Vesting of early exercised stock options Adjustments To Additional Paid In Capital Share Based Compensation Vesting Of Early Exercised Stock Options Adjustments to additional paid in capital share based compensation vesting of early exercised stock options. Current Fiscal Year End Date Current Fiscal Year End Date Less than 12 months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table [Member] Weighted-average grant date fair value Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value [Abstract] Shares available for grant under the stock plans (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Statement [Table] Statement [Table] Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Collaboration Agreements Collaborative Arrangement Disclosure [Text Block] Cash flows from financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Equity Awards Adjustments, Excluding Value Reported in Compensation Table Equity Awards Adjustments, Excluding Value Reported in the Compensation Table [Member] Total Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Additional payment received to exercise option to expand number of targets Additional Payment Received To Exercise Option To Expand Number Of Targets Additional payment received to exercise option to expand number of targets. Recorded deferred revenue Contract with Customer, Liability Anti-dilutive securities excluded from computation of diluted net loss per share (in shares) Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Denominator: Weighted Average Number of Shares Outstanding, Diluted [Abstract] All Adjustments to Compensation All Adjustments to Compensation [Member] Amendment Flag Amendment Flag Sale price of stock (in USD per share) Sale of Stock, Price Per Share Other Commitments [Table] Other Commitments [Table] Termination Date Trading Arrangement Termination Date Net cash provided by financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Insider Trading Policies and Procedures Adopted Insider Trading Policies and Procedures Adopted [Flag] Measure: Measure [Axis] Schedule of Activity under 2020 Plan and 2012 Plan Share-Based Payment Arrangement, Option, Activity [Table Text Block] Research and development milestone payments Revenue, Remaining Performance Obligation, Variable Consideration Amount, Research And Development Milestones Revenue, Remaining Performance Obligation, Variable Consideration Amount, Research And Development Milestones Long-Lived Tangible Asset Long-Lived Tangible Asset [Domain] Schedule of Investments Fair Value Measurement on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Weighted-average number of shares outstanding, basic (in shares) Weighted Average Number of Shares Outstanding, Basic Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Schedule of Computation of Basic and Diluted Net Loss per Share Attributable to Common Stockholders Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Related Party Transaction [Domain] Related Party Transaction [Domain] Pay vs Performance Disclosure, Table Pay vs Performance [Table Text Block] Operating lease expenses, excluding variable lease payments Operating Lease, Expense Forgone Recovery due to Violation of Home Country Law, Amount Forgone Recovery due to Violation of Home Country Law, Amount Entity Tax Identification Number Entity Tax Identification Number Weighted-average price per share (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Per Share Weighted Average Price of Shares Purchased Weighted-average exercise price, beginning balance (in USD per share) Weighted-average exercise price, ending balance (in USD per share) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Forgone Recovery due to Expense of Enforcement, Amount Forgone Recovery due to Expense of Enforcement, Amount Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Common stock, par value (in USD per share) Common Stock, Par or Stated Value Per Share Common stock, shares issued (in shares) Common Stock, Shares, Issued Warrants offering expenses Warrants Offering Expenses Warrants offering expenses. Number of performance obligations Number Of Performance Obligations Number Of Performance Obligations Options granted (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Use of Estimates Use of Estimates, Policy [Policy Text Block] Trading Arrangement: Trading Arrangement [Axis] Total Shareholder Return Amount Total Shareholder Return Amount Insider Trading Arrangements [Line Items] Proceeds from issuance of warrants Proceeds from Issuance of Warrants Security Exchange Name Security Exchange Name Weighted-average exercise price, options forfeited (in USD per share) Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price Number of RSUs Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding [Roll Forward] Tenant improvements Tenant Improvements Allowance for credit losses Debt Securities, Available-for-Sale, Allowance for Credit Loss, Excluding Accrued Interest Maximum increase or decrease percentage of warrants Maximum Increase Or Decrease Percentage Of Warrants Maximum increase or decrease percentage of warrants. Total liabilities Liabilities Antidilutive Securities, Name Antidilutive Securities, Name [Domain] Purchase price of warrants (in USD per share) Class Of Warrant Or Right, Purchase Price Of Warrants Or Rights Class Of Warrant Or Right, Purchase Price Of Warrants Or Rights Additions to property and equipment included in accounts payable and accrued expenses and other current liabilities Capital Expenditures Incurred but Not yet Paid At the Market Offering At The Market Offerings [Member] At the market offerings. Marketable securities, current Estimated fair value, short-term Debt Securities, Available-for-Sale, Excluding Accrued Interest, Current Pension Adjustments Prior Service Cost Pension Adjustments Prior Service Cost [Member] Maturities of marketable securities Proceeds from Sale and Maturity of Debt Securities, Available-for-Sale Repurchase of unvested early exercised stock (in shares) Stock Repurchased During Period, Shares Operating expenses: Operating Expenses [Abstract] Material Terms of Trading Arrangement Material Terms of Trading Arrangement [Text Block] Other Other Liabilities, Current Revenue recognized Contract With Customer Liability Revenue Recognized Excluding Opening Balance Contract With Customer Liability Revenue Recognized Excluding Opening Balance Issuance of common stock and pre-funded warrants in connection with equity financing, net of issuance costs Stock Issued During Period, Value, New Issues Statement [Line Items] Statement [Line Items] Rule 10b5-1 Arrangement Adopted Rule 10b5-1 Arrangement Adopted [Flag] Cash and cash equivalents Cash and cash equivalents Cash and Cash Equivalent Counterparty Name Counterparty Name [Axis] Schedule of RSU Activity Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Common stock Common Stock [Member] RSUs vested (in shares) Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Non-NEOs Non-NEOs [Member] Net (decrease) increase in cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Healthcare Plan Provider Trust for Benefit of Employees [Member] Accrued professional services Accrued Professional Fees, Current