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  <xs:element id="nrix_AtTheMarketFinancingMember" abstract="true" name="AtTheMarketFinancingMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_PublicOffering2024Member" abstract="true" name="PublicOffering2024Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_AtTheMarketOfferingsMember" abstract="true" name="AtTheMarketOfferingsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationVestingOfEarlyExercisedStockOptions" abstract="false" name="AdjustmentsToAdditionalPaidInCapitalShareBasedCompensationVestingOfEarlyExercisedStockOptions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_ProceedsFromIssuanceOfCommonStockAndWarrants" abstract="false" name="ProceedsFromIssuanceOfCommonStockAndWarrants" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_PaymentsForRepurchaseOfStockOptions" abstract="false" name="PaymentsForRepurchaseOfStockOptions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_DeferredIssuanceCostsIncludedInAccruedExpensesAndOtherLiabilities" abstract="false" name="DeferredIssuanceCostsIncludedInAccruedExpensesAndOtherLiabilities" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_DeferredIssuanceCostsRecognizedRelatedToEquityFinancing" abstract="false" name="DeferredIssuanceCostsRecognizedRelatedToEquityFinancing" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_VestingOfEarlyExercisedStockOptions" abstract="false" name="VestingOfEarlyExercisedStockOptions" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_OtherRisksAndUncertaintiesPolicyTextBlock" abstract="false" name="OtherRisksAndUncertaintiesPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="nrix_ScheduleOfAccruedExpensesAndOtherCurrentLiabilitiesTableTableTextBlock" abstract="false" name="ScheduleOfAccruedExpensesAndOtherCurrentLiabilitiesTableTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="nrix_ScheduleOfCommonStockSharesReservedForFutureIssuanceTableTableTextBlock" abstract="false" name="ScheduleOfCommonStockSharesReservedForFutureIssuanceTableTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="nrix_OrganizationConsolidationAndPresentationOfFinancialStatementsTable" abstract="true" name="OrganizationConsolidationAndPresentationOfFinancialStatementsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="nrix_EquityDistributionAgreementMember" abstract="true" name="EquityDistributionAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_PiperSandlerAndCoMember" abstract="true" name="PiperSandlerAndCoMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_RegisteredDirectOfferingsMember" abstract="true" name="RegisteredDirectOfferingsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_PreFundedWarrantsMember" abstract="true" name="PreFundedWarrantsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_OrganizationConsolidationAndPresentationOfFinancialStatementsLineItems" abstract="true" name="OrganizationConsolidationAndPresentationOfFinancialStatementsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="nrix_SaleOfStockCommonStockRemainingAvailableForSale" abstract="false" name="SaleOfStockCommonStockRemainingAvailableForSale" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_CommissionPercentageOnGrossSalesPriceOfShares" abstract="false" name="CommissionPercentageOnGrossSalesPriceOfShares" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="nrix_ClassOfWarrantOrRightPurchasePriceOfWarrantsOrRights" abstract="false" name="ClassOfWarrantOrRightPurchasePriceOfWarrantsOrRights" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:perShareItemType"/>
  <xs:element id="nrix_WarrantsOfferingExpenses" abstract="false" name="WarrantsOfferingExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_StockIssuedDuringPeriodValueNewIssuesAndAdjustmentsToAdditionalPaidInCapitalWarrantIssued" abstract="false" name="StockIssuedDuringPeriodValueNewIssuesAndAdjustmentsToAdditionalPaidInCapitalWarrantIssued" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_GileadAgreementMember" abstract="true" name="GileadAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_SanofiAgreementMember" abstract="true" name="SanofiAgreementMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_PfizerMember" abstract="true" name="PfizerMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_NumberOfSpecifiedDrugTargets" abstract="false" name="NumberOfSpecifiedDrugTargets" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_CollaborationAgreementContractTerm" abstract="false" name="CollaborationAgreementContractTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="nrix_CollaborationAgreementContractTermExtension" abstract="false" name="CollaborationAgreementContractTermExtension" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="nrix_ProceedsFromCollaborationAgreementExtensionPayment" abstract="false" name="ProceedsFromCollaborationAgreementExtensionPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_NumberOfDrugCandidates" abstract="false" name="NumberOfDrugCandidates" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_UpfrontPayment" abstract="false" name="UpfrontPayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_UpfrontPaymentOfAdditionalFees" abstract="false" name="UpfrontPaymentOfAdditionalFees" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_ResearchMilestonesPaymentsReceived" abstract="false" name="ResearchMilestonesPaymentsReceived" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_ProceedsFromCollaborationAgreementClinicalMilestonePayment" abstract="false" name="ProceedsFromCollaborationAgreementClinicalMilestonePayment" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_AdditionalPayments" abstract="false" name="AdditionalPayments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_RevenueRemainingPerformanceObligationVariableConsiderationAmountResearchAndDevelopmentMilestones" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmountResearchAndDevelopmentMilestones" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_RevenueRemainingPerformanceObligationVariableConsiderationAmountTargetLicensingAndReservation" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmountTargetLicensingAndReservation" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_RevenueRemainingPerformanceObligationVariableConsiderationAmountCertainSalesMilestones" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmountCertainSalesMilestones" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_CollaborationAgreementExpirationTerm" abstract="false" name="CollaborationAgreementExpirationTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="nrix_VariableConsiderationIncludedInTransactionPrice" abstract="false" name="VariableConsiderationIncludedInTransactionPrice" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_AdditionalPaymentReceivedToExerciseOptionToExpandNumberOfTargets" abstract="false" name="AdditionalPaymentReceivedToExerciseOptionToExpandNumberOfTargets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_ContractualExtendedResearchPeriod" abstract="false" name="ContractualExtendedResearchPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="nrix_RevenueRemainingPerformanceObligationVariableConsiderationAmountRegulatoryMilestones" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmountRegulatoryMilestones" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_NumberOfPerformanceObligations" abstract="false" name="NumberOfPerformanceObligations" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_NumberOfAdditionalSpecifiedDrugTargets" abstract="false" name="NumberOfAdditionalSpecifiedDrugTargets" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_ContractualInitialResearchPeriod" abstract="false" name="ContractualInitialResearchPeriod" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="nrix_ContractWithCustomerLiabilityRevenueRecognizedExcludingOpeningBalance" abstract="false" name="ContractWithCustomerLiabilityRevenueRecognizedExcludingOpeningBalance" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_NumberOfProductsArisingFromCollaboration" abstract="false" name="NumberOfProductsArisingFromCollaboration" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_LaboratoryEquipmentMember" abstract="true" name="LaboratoryEquipmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_SoftwareInProgressMember" abstract="true" name="SoftwareInProgressMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_AccruedContractResearchAndLabSupplies" abstract="false" name="AccruedContractResearchAndLabSupplies" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_AccruedClinicalCurrent" abstract="false" name="AccruedClinicalCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_AccruedAndOtherLiabilitiesCurrent" abstract="false" name="AccruedAndOtherLiabilitiesCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_DebtSecuritiesAvailableForSaleAccumulatedGrossUnrealizedGainBeforeTaxCurrent" abstract="false" name="DebtSecuritiesAvailableForSaleAccumulatedGrossUnrealizedGainBeforeTaxCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_DebtSecuritiesAvailableForSaleAccumulatedGrossUnrealizedLossBeforeTaxCurrent" abstract="false" name="DebtSecuritiesAvailableForSaleAccumulatedGrossUnrealizedLossBeforeTaxCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_TransfersOfFinancialInstrumentsBetweenValuationLevels" abstract="false" name="TransfersOfFinancialInstrumentsBetweenValuationLevels" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_ImpairmentLossOnMarketableSecurities" abstract="false" name="ImpairmentLossOnMarketableSecurities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_ThirdAmendmentMember" abstract="true" name="ThirdAmendmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_BrisbaneCaliforniaMember" abstract="true" name="BrisbaneCaliforniaMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_AreaOfOfficeSpaceLeased" abstract="false" name="AreaOfOfficeSpaceLeased" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:areaItemType"/>
  <xs:element id="nrix_OperatingLeaseRentPayableAdjustmentPerMonth" abstract="false" name="OperatingLeaseRentPayableAdjustmentPerMonth" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="nrix_LesseeOperatingLeaseNumberOfRenewalOptions" abstract="false" name="LesseeOperatingLeaseNumberOfRenewalOptions" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_CommonStockVotingRightsForShareholders" abstract="false" name="CommonStockVotingRightsForShareholders" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="nrix_MinimumCommonStockHoldingPercentage" abstract="false" name="MinimumCommonStockHoldingPercentage" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="nrix_MaximumIncreaseOrDecreasePercentageOfWarrants" abstract="false" name="MaximumIncreaseOrDecreasePercentageOfWarrants" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
  <xs:element id="nrix_EquityIncentivePlansMember" abstract="true" name="EquityIncentivePlansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_TwoThousandTwentyFourEquityInducementPlanMember" abstract="true" name="TwoThousandTwentyFourEquityInducementPlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="nrix_StockPlansAndEmployeeStockPurchasePlanMember" abstract="true" name="StockPlansAndEmployeeStockPurchasePlanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
